STRUCTURE AND FUNCTION OF PEPTIDES AND PROTEIN
The objectives of this research group are:
- Molecular characterization of enzymes and development of applications in industrial, environmental and clinical fields.
- Study of monooxygenase complex and their use in bioremediation of aromatic compounds.
- Use of enzymes and microbial cells for the biotransformation of molecules of biotechnological interest.
- Analysis of antioxidant systems for the evaluation of oxidative stress and their applications in the field of pharmacology.
- Study of bioactive peptide/peptidomimetic (with antimicrobial activity, antitumor, antiviral, immunomodulatory and anti-inflammatory effects) and proteins that release bioactive peptides.
- Study of the cellular response to DNA damage related to neoplastic transformation and apoptosis.
- Analysis of ADP-ribosylation system in different organisms.
- Molecular study of proteins involved in the pathogenesis of genetic diseases and drug development.
The main international collaborations are with: the Department of Biology of the University of Copenhagen; Centro de Biologia Molecular Severo Ochoa; Universidad Autonoma de Madrid; Department of Chemistry, University of Cambridge; Department of Infectious Diseases and Immunology – University of Utrecht.
Partecipants
- BARTOLUCCI SIMONETTA (Full Professor)
- CUBELLIS MARIA VITTORIA (Full Professor)
- DI DONATO ALBERTO (Full Professor)
- MORACCI MARCO (Full Professor)
- FARAONE MENNELLA MARIA ROSARIA (Associate Professor)
- CAFARO VALERIA (Researcher)
- CONTURSI PATRIZIA (Researcher)
- DE MAIO ANNA (Researcher)
- FIORENTINO GABRIELLA (Researcher)
- GUAGLIARDI ANNAMARIA (Researcher)
- LIMAURO DANILA (Researcher)
- MEROLA MARCELLO (Researcher)
- NOTOMISTA EUGENIO (Researcher)
- PIZZO ELIODORO (Researcher)
- STRAZZULLI ANDREA (Researcher)