Federico II and Bristol Universities research on new synthetic biological components

A new type of synthetic biological components that can be externally regulated to better fit their host cells. That, in a nutshell, is the result of work proposed by researchers at the Federico II University and theUniversity of Bristol and recently published in the prestigious international journal Nature Communications.

This result will allow the construction of new robust and better performing biological circuits with enormous application potential in biotechnology and for the development of new therapies. The research involved the collaboration of Professor Mario di Bernardo of the Frederican Department of Electrical Engineering and Information Technology with Dr. Thomas Gorochowski and his group at the University of Bristol in the United Kingdom under the international cooperation agreement linking the two universities.

The work was carried out as part of the European FET-OPEN COSY-BIO project led by the Telethon Foundation.

Bartoli V., Meaker G.A., di Bernardo M & Gorochowski T.E. (2020)"Tunable genetic devices through simultaneous control of transcription and translation," Nature Communications. (DOI: 10.1038/s41467-020-15653-7).