STRUCTURE AND FUNCTION OF PEPTIDES AND PROTEIN

The objectives of this research group are:

  • Molecular characterization of enzymes and development of applications in industrial, environmental and clinical fields.
  • Study of monooxygenase complex and their use in bioremediation of aromatic compounds.
  • Use of enzymes and microbial cells for the biotransformation of molecules of biotechnological interest.
  • Analysis of antioxidant systems for the evaluation of oxidative stress and their applications in the field of pharmacology.
  • Study of bioactive peptide/peptidomimetic (with antimicrobial activity, antitumor, antiviral, immunomodulatory and anti-inflammatory effects) and proteins that release bioactive peptides.
  • Study of the cellular response to DNA damage related to neoplastic transformation and apoptosis.
  • Analysis of ADP-ribosylation system in different organisms.
  • Molecular study of proteins involved in the pathogenesis of genetic diseases and drug development.

The main international collaborations are with: the Department of Biology of the University of Copenhagen; Centro de Biologia Molecular Severo Ochoa; Universidad Autonoma de Madrid; Department of Chemistry, University of Cambridge; Department of Infectious Diseases and Immunology – University of Utrecht.

Partecipants

  • BARTOLUCCI SIMONETTA (Full Professor)
  • CUBELLIS MARIA VITTORIA (Full Professor)
  • DI DONATO ALBERTO (Full Professor)
  • MORACCI MARCO (Full Professor)
  • FARAONE MENNELLA MARIA ROSARIA (Associate Professor)
  • CAFARO VALERIA (Researcher)
  • CONTURSI PATRIZIA (Researcher)
  • DE MAIO ANNA (Researcher)
  • FIORENTINO GABRIELLA (Researcher)
  • GUAGLIARDI ANNAMARIA (Researcher)
  • LIMAURO DANILA (Researcher)
  • MEROLA MARCELLO (Researcher)
  • NOTOMISTA EUGENIO (Researcher)
  • PIZZO ELIODORO (Researcher)
  • STRAZZULLI ANDREA (Researcher)